Marine magnesium: benefits, B6, blood pressure, effects, and timing
“Marine magnesium” refers to magnesium extracted from seawater. On labels, it is most often provided as chloride, hydroxide, or oxide salts. The “marine” origin is not itself a chemical form; tolerance and absorption depend mainly on the salt and dose — see the differences in absorption by salt.
What exactly is marine magnesium and how is it obtained?
It is produced by concentrating/evaporating seawater and purifying the result. You end up with inorganic salts (most commonly chloride/hydroxide/oxide). The “marine” claim does not imply superior absorption; it describes the source (seawater), not the form.
“Marine” = origin (seawater). “Citrate,” “bisglycinate,” “oxide,” etc. = chemical forms. Bioavailability depends mostly on the form, not the origin. For instance, oxide is less well absorbed than chloride, lactate, or aspartate at equivalent elemental doses.
Expected benefits and limits based on current evidence
- Magnesium supports energy metabolism, neuromuscular function, and electrolyte balance — summarized in the NIH ODS factsheet.
- Recommended intakes in adults are about 300–380 mg/day, with details in intake references.
- GI tolerance varies by dose and form (osmotic laxative effect at high doses), see laxative effect notes.
For an overview (roles, needs, sources), see our magnesium guide.
Marine magnesium vs common forms
The table below summarizes practical markers of bioavailability/content/tolerance. Reminder: “marine” is a source; these products typically contain chloride/hydroxide/oxide.
| # | Magnésium | Biodisponibilité | Teneur Mg | Inconvénient |
|---|---|---|---|---|
| 1 | Bisglycinate | Very high | ≈14–20% | Larger capsules |
| 2 | Glycerophosphate | Very high | ≈12–13% | - |
| 3 | Malate | Very high | ≈11% | Lower concentration |
| 4 | Taurinate | Very high | ≈6% | Lower concentration |
| 5 | Citrate | Very high | ≈16% | Laxative at high dose |
| 6 | Lactate | High | ≈12% | Laxative at high dose |
| 7 | Chloride | Fairly high | ≈12% | Variable tolerance |
| 8 | Sulfate | Fairly high | ≈12% | Laxative effect |
| 9 | Oxide | Low | ≈60% | Low absorption, laxative |
| 10 | Marine (source) | Variable | Variable | Often oxide/chloride; absorption depends on the actual salt |
See the magnesium guide for definitions and context.
Tolerance, side effects, and everyday precautions
Common, dose‑dependent effects: diarrhea, abdominal cramps, bloating, nausea. They usually recede with dose reduction/splitting; see magnesium side effects.
Warning situations (rarer): signs of hypermagnesemia, especially with renal impairment or very high intakes; clinical markers are summarized in hypermagnesemia and serum magnesium testing.
Separate magnesium by 2–4 hours from certain antibiotics (quinolones, tetracyclines) and thyroid hormones (levothyroxine) — see the reference factsheet.
Start low (200–300 mg/day of elemental magnesium), split (AM/PM), take with a meal, and adjust to effect/tolerance. If discomfort appears, reduce dose or switch forms.
For excess, see magnesium overdose.
Marine magnesium with vitamin B6: common pairing and reality check
Many products combine marine magnesium + vitamin B6. B6 supports the nervous system and may help reduce fatigue; the idea that B6 improves magnesium absorption is not robustly documented. Product quality depends far more on the magnesium form, dose, and individual tolerance. Check potential overlaps in the interactions section.
Marine magnesium and blood pressure: what summaries say
In adults, meta‑analyses suggest a modest effect of magnesium supplementation on blood pressure in some populations, with heterogeneity across dose/duration/forms. Recommendations remain cautious; prioritize a well‑tolerated, split form. General safety upper limits (from supplements) are around 250 mg/day (EFSA) and 350 mg/day (NIH). Seek medical advice if you are on antihypertensives.
When to take marine magnesium for better tolerance
- Prefer with a meal to limit GI discomfort
- Split AM/PM for higher total intakes
- If aiming for relaxation/sleep, try dosing 2–3 hours before bedtime
For timing/tolerance pointers, see citrate and bisglycinate.
Key takeaways and common questions
- Marine + B6: frequent pairing for nervous system and fatigue; no strong proof of superior magnesium absorption
- Side effects: mainly digestive, dose‑dependent; see magnesium side effects
- When to take: with meals, split as needed; try 2–3 h before bed for relaxation
- Hypertension: effects modest/variable; seek medical advice if treated
- Label check: confirm elemental magnesium, form (chloride/oxide, etc.), excipients, and separation from sensitive meds




